Skip to main content
Assets
CRISPR Therapeutics logo
CRSP.NASDAQ
CRISPR Therapeutics
Health Care · Biotechnology

Gene editing company developing transformative therapies using CRISPR/Cas9 technology for genetic diseases and cancer.

HQ: SwitzerlandListed: United States

Historical AI Forecasts

Audit every published iPulse AI forecast batch and immutable historical research document for CRISPR Therapeutics.

CRISPR Therapeutics AG (CRSP.NASDAQ) AI FORECASTS & ADVISOR ANALYSIS

Read and compare the 12 individual AI Advisor deep-dive reports, including their forecast paths, ratings, price targets, and reasoning.

Updated on 5 June 2026Deep analysis 5 June 2026

25 min readAudit All Past Forecasts
Elon Musk AI advisor icon

Elon Musk AI

The Visionary FrameworkAI Thinker

Model rating

Strong Buy

5-Year Return Est.

+331.0%

CRSP.NASDAQ does not currently pay dividends

1. Investment Thesis — Base Case

CRISPR Therapeutics is a classic Paradigm Shifter currently traversing the trough of disillusionment before its secondary exponential S-curve. The company has already de-risked the fundamental physics of gene editing with its first commercial approval, yet the market prices it for failure due to a myopic focus on initial rollout friction and trailing earnings. The $2 billion cash position is the ultimate asymmetric advantage, providing at least 4-5 years of runway to finalize the transition to scalable in-vivo therapeutics and allogeneic oncology platforms without dilutive capital constraints. As AI convergence accelerates their R&D velocity, the will radically improve.

  • In-vivo transition fundamentally expands the from rare to chronic diseases.
  • ensures survival and despite high R&D burn.
  • AI modeling convergence compresses execution timelines and mitigates off-target physical risks.
  • Geopolitical BIOSECURE mandates funnel sovereign and private capital toward allied genomic leaders.
  • Current $5 billion market cap is completely disconnected from the trillion-dollar future of programmable medicine.

Historical prices and published forecast

Historical prices and published forecastObserved prices and the selected advisor's published projection share a split-adjusted price basis. Prices after the forecast start are later observations, not information known at publication. Forecasts are uncertain. Values in USD.11.0775138.93202.85266.78Jun 2021Dec 2023Jun 2026Dec 2028Jun 2031Forecast starts
  • Observed price
  • Published advisor forecast
Observed prices and the selected advisor's published projection share a split-adjusted price basis. Prices after the forecast start are later observations, not information known at publication. Forecasts are uncertain. Values in USD.
View chart values
Historical prices and published forecast — published chart values
SeriesDateValue (USD)
Observed price2021-06-03114
Observed price2021-06-27148
Observed price2021-07-01159
Observed price2021-07-25120
Observed price2021-07-29119
Observed price2021-08-06137
Observed price2021-09-03122
Observed price2021-09-19117
Observed price2021-09-23117
Observed price2021-10-1796.8
Observed price2021-10-2197.0
Observed price2021-11-1485.8
Observed price2021-11-1884.3
Observed price2021-12-0474.0
Observed price2021-12-2081.0
Observed price2022-01-0968.6
Observed price2022-01-1368.8
Observed price2022-01-2961.3
Observed price2022-02-1061.9
Observed price2022-02-2254.3
Observed price2022-03-1460.4
Observed price2022-04-0367.8
Observed price2022-04-0763.9
Observed price2022-05-0151.1
Observed price2022-05-0943.2
Observed price2022-05-2958.2
Observed price2022-06-1459.0
Observed price2022-06-1868.0
Observed price2022-06-3060.8
Observed price2022-07-1683.5
Observed price2022-08-0980.1
Observed price2022-08-2167.8
Observed price2022-09-0662.8
Observed price2022-09-1472.2
Observed price2022-10-0465.7
Observed price2022-10-1655.5
Observed price2022-11-0948.9
Observed price2022-11-1360.7
Observed price2022-11-1757.6
Observed price2022-12-0750.6
Observed price2022-12-1548.3
Observed price2022-12-3140.6
Observed price2023-01-1249.1
Observed price2023-02-0555.5
Observed price2023-02-1351.5
Observed price2023-02-2548.3
Observed price2023-03-0945.6
Observed price2023-03-2543.5
Observed price2023-04-0644.9
Observed price2023-04-1851.9
Observed price2023-05-0453.1
Observed price2023-05-2465.9
Observed price2023-06-0564.7
Observed price2023-06-2555.9
Observed price2023-07-0754.9
Observed price2023-07-1157.6
Observed price2023-07-2757.1
Observed price2023-08-2047.7
Observed price2023-08-2850.4
Observed price2023-09-1749.0
Observed price2023-09-2146.1
Observed price2023-10-0742.8
Observed price2023-10-2738.7
Observed price2023-11-0854.7
Observed price2023-11-1659.2
Observed price2023-11-2072.2
Observed price2023-12-1865.6
Observed price2023-12-2261.5
Observed price2024-01-1962.0
Observed price2024-01-2366.2
Observed price2024-02-0868.8
Observed price2024-02-2886.7
Observed price2024-03-0779.9
Observed price2024-03-3166.3
Observed price2024-04-0465.1
Observed price2024-04-2853.5
Observed price2024-05-0657.1
Observed price2024-05-1051.2
Observed price2024-05-3053.8
Observed price2024-06-1562.8
Observed price2024-07-0553.6
Observed price2024-07-1759.5
Observed price2024-07-2956.8
Observed price2024-08-1047.3
Observed price2024-09-0745.1
Observed price2024-09-1549.4
Observed price2024-09-1949.5
Observed price2024-10-0545.2
Observed price2024-10-2547.4
Observed price2024-11-1051.2
Observed price2024-11-1446.9
Observed price2024-11-3051.2
Observed price2024-12-1245.8
Observed price2024-12-2839.9
Observed price2025-01-1338.9
Observed price2025-01-2143.5
Observed price2025-02-1039.6
Observed price2025-02-1852.2
Observed price2025-03-1043.3
Observed price2025-03-3035.1
Observed price2025-04-0732.4
Observed price2025-04-1139.3
Observed price2025-05-0534.4
Observed price2025-05-1738.9
Observed price2025-05-2936.8
Observed price2025-06-2245.3
Observed price2025-06-2647.6
Observed price2025-07-2065.5
Observed price2025-07-2466.1
Observed price2025-08-0555.6
Observed price2025-08-2951.8
Observed price2025-09-1457.4
Observed price2025-09-1860.7
Observed price2025-10-0872.8
Observed price2025-10-2071.5
Observed price2025-11-0955.1
Observed price2025-11-2149.8
Observed price2025-12-0757.0
Observed price2025-12-1158.1
Observed price2025-12-3153.4
Observed price2026-01-0856.4
Observed price2026-02-0151.8
Observed price2026-02-0948.8
Observed price2026-03-0159.1
Observed price2026-03-0958.8
Observed price2026-03-2946.7
Observed price2026-04-0249.5
Observed price2026-04-1857.4
Observed price2026-05-1253.4
Observed price2026-05-1648.2
Observed price2026-05-2856.4
Observed price2026-06-1351.4
Observed price2026-07-0760.8
Observed price2026-07-1947.3
Observed price2026-07-2746.7
Observed price2026-08-1654.0
Observed price2026-08-2058.1
Observed price2026-09-1453.0
Observed price2026-09-1551.8
Observed price2026-09-1757.3
Observed price2026-09-1856.6
Published advisor forecast2026-06-0457.0
Published advisor forecast2026-09-0459.8
Published advisor forecast2026-12-0455.0
Published advisor forecast2027-03-0461.6
Published advisor forecast2027-06-0466.5
Published advisor forecast2027-09-0476.5
Published advisor forecast2027-12-0484.2
Published advisor forecast2028-03-0480.0
Published advisor forecast2028-06-0494.4
Published advisor forecast2028-09-04106
Published advisor forecast2028-12-04114
Published advisor forecast2029-03-04107
Published advisor forecast2029-06-04123
Published advisor forecast2029-09-04136
Published advisor forecast2029-12-04155
Published advisor forecast2030-03-04149
Published advisor forecast2030-06-04166
Published advisor forecast2030-09-04180
Published advisor forecast2030-12-04207
Published advisor forecast2031-03-04227
Published advisor forecast2031-06-04245

2. Scenarios & Signals

Bull case

If the base case accelerates and in-vivo delivery physics are fully mastered across multiple tissue types, the S-curve goes strictly vertical. A breakthrough in allogeneic solid-tumor CAR-T therapy triggers immediate revaluation. The company shifts from a single-product commercial entity to the dominant infrastructure layer for human genomic editing. Partnering with major sovereign defense and health agencies, the expands exponentially, pushing the valuation toward $20B-$30B. The physics strictly supports this reality if the biological delivery bottleneck is solved.

Bear case

If biological delivery constraints remain physically insurmountable and next-generation prime/base editors rapidly commoditize Cas9, CRISPR becomes a . The S-curve stalls. High TTM depletes the faster than can replenish it in a constrained sovereign health budget environment. Forced in a punishing rate regime permanently traps the equity price in the $20-$30 range, reducing the company to an incremental optimizer struggling within a paradigm it helped create.

Current crowd narrative

The crowd currently views CRISPR Therapeutics as a binary, one-trick pony struggling with the agonizingly slow commercial rollout of . Wall Street analysts are anchored to negative trailing earnings, massive R&D burn, and the friction of high-cost ex-vivo manufacturing. The prevailing media narrative dismisses the broader pipeline, categorizing the stock as an overhyped pandemic-era relic that faces impossible pricing headwinds from sovereign healthcare budgets and rising competition from . They believe the S-curve has already matured.

Alpha-gap assessment

The lies in understanding the difference between a boutique pharmaceutical product and a foundational biological operating system. The crowd prices CRISPR based on near-term reimbursement metrics; I evaluate it based on the impending of their in-vivo platform. By successfully integrating AI-driven protein modeling with their CRISPR architecture, they are solving the physical constraints of delivery at an accelerating rate. The $2 billion is completely ignored by the market, yet it guarantees without . The crowd is missing the transition from artisanal ex-vivo treatments to scalable, software-like in-vivo therapeutics.

Convergence catalyst

The will violently close upon the release of definitive Phase 1/2 clinical data for their in-vivo cardiovascular or oncology targets (e.g., CTX310/320) demonstrating absolute lipid reduction or tumor regression with zero off-target toxicity. This catalyst, expected within 12-18 months, mathematically proves the platform's scalability.

Complete advisor preview locked

Unlock this report and every AI Advisor

Sign in to check your access, or upgrade to the Base plan to read this report and open every advisor.